Pediatrics in Review
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Caring for the Child with Cancer and the Family: Lessons Learned From Children With Acute Leukemia

Olle Jane Sahler MD1
 1 Associate Professor of Pediatrics, Psychiatry, Medical Humanities, and Medical Informatics, University of Rochester School of Medicine and Dentistry, Rochester, New York

In a report appearing in 1951, Southam et al1 reported on the natural history of 173 patients with acute leukemia treated supportively at Memorial Center for Cancer and Allied Diseases in New York City from 1926 to 1948. The study population included 65 children less than 10 years of age. The average length of survival of these patients was 19.3 weeks after the onset of symptoms attributable to leukemia. Of the entire sample of patients irrespective of age, only 4 (2.3%) survived 52 weeks or beyond.

In 1948, Memorial Center began treating patients with folic acid or purine antagonists and steroids.






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Pediatrics Pediatrics in Review
Copyright © 1990 by the American Academy of Pediatrics.