Erratum
Regarding the article on Pencillin in Pediatrics in Review. 1995;16:83-90 (March), a reader expressed concern about the answers to the first and second questions in the PIR Quiz. In the first question, the clinical picture presented was clearly meningococcemia, and aqueous penicillin G IV is the drug of choice. However, as Dr. Feigin states, "Given the choices in question #2, we would probably choose methicillin because the question suggests that Staphylococcus aureus may be the offending organism. Of the various semisynthetic penicillin derivatives listed, methicillin is the one with the lowest degree of protein binding (20%) and, thus, is least likely to displace bilirubin from albumin binding sites. Therefore, its use in the newborn period may be indicated."
