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Fever and Host Responses

Editors: Henry M. Adam, MD.

Even though fever, as part of the inflammatory response, is only a sign of an underlying pathologic stress, we seem to have the need to treat it with a drug or a sponge, as if it were the noxious culprit itself. In contrast to hyperthermia, fever rarely poses any threat to a child's well-being; in fact, it has been argued that as an energy-expensive process, it is not likely to have weathered evolution without conferring some survival benefit. Because fever is the most frequent signal of illness in children, serving as the chief complaint for as many as one third of all pediatric office visits, we do well to understand fever as a phenomenon distinct from the illnesses that cause it.

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