Human Immune Serum Globulins
In the November issue of PIR (4:135, 1982), on p 140 under "Hepatitis B Immune Globulin (HBIG), Recommendation," the next to the last paragraph states: "In newborns with a possible exposure to hepatitis B, a dose of 0.5 ml/kg of HBIG is recommended." This recommended dose is much too large for a newborn. The dose recommended is a total dose of 0.5 ml IM, to be given as soon after birth as possible (no later than 24 hours). The same dose (0.5 ml) should be repeated three months and six months later.
