Cystic Fibrosis: Current Approach to Diagnosis and Management
William B. Wheeler MD1
Harvey R. Colten MD2
1 Assistant Professor of Pediatrics, Washington University School of Medicine, and Director of the Pulmonary Function Laboratory at Children's Hospital, St Louis
2 Harriet B. Spoehrer Professor and Chairman of the Department of Pediatrics, Washington University School of Medicine
Major advances have been made in understanding the basic abnormalities in cystic fibrosis, in DNA technology and genetic research, and in basic treatment of the patient with cystic fibrosis. As our knowledge of the pathophysiology of the disease increases, our care becomes more sophisticated and the patients survive longer. As larger numbers of adults with cystic fibrosis survive, an entirely new set of problems have been encountered and must be solved.