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(Pediatrics in Review. 1997;18:67-69.)
© 1997 American Academy of Pediatrics
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Minerals are inorganic elements essential to the diet. Some of these elements are required in large amounts, such as calcium and phosphorus. Otherstrace elements such as zinc, copper, and manganeseare required in minute amounts.
The protein constituents of
standard milk-based formulas are found in complexes with some of the major
minerals (eg, Na, Cl, K, Ca, Mg, and P). In general, most formulas contain
larger amounts of minerals than does human milk (Table 2
).
However, more
important than the concentration of minerals in the formula is their
bioavailability, which refers to their degree of absorption and utilization.
Minerals that are not sufficiently bioavailable must be supplemented to meet
the nutritional needs of the infant. In commercial infant formulas (both cow
milk- and soy-based), limited bioavailability and low mineral density of
certain minerals have led the manufacturers to add inorganic salts of those
minerals. These salts form complexes with ligands such as casein,
phytoferritin, and citrate, which may bind excessively.
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Our understanding
of the bioavailability of specific minerals has grown because of the
substantial improvement in the techniques used to assess mineral absorption,
metabolism, distribution, and excretion.
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