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Although the precise etiology of pyloric stenosis remains unknown, there is some evidence that it may be an acquired condition, rather than a congenital disorder, as previously thought. In this condition, gastric outlet obstruction results from hypertrophy of the pyloric muscle, edema of the pyloric canal, and spasm of the antropyloric muscle, which leads to vomiting, dehydration, and metabolic alkalosis.
Clinical manifestations of pyloric
stenosis begin at a mean age of
3 weeks after birth, but they may
occur at any time between birth and
5 months of age. The onset of
clinical symptoms is heralded by
regurgitation of feeds and progresses to
the classic nonbilious vomiting,
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