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| Case 1 Presentation |
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He has had fevers since yesterday, chills today, nausea and a decreased appetite for 1 week, but no vomiting or diarrhea. He had a mild sore throat 2 weeks ago. A red rash started yesterday on his right knee and appeared briefly on his neck. The boy lives with his mother; they have hamsters, guinea pigs, a cat, a dog, and a pet rat, purchased just 2 days ago.
The patient had unprotected heterosexual sex 2 months ago. He denies dysuria, frequency, penile discharge, or a history of sexually transmitted disease. His sister has "small joint" rheumatoid arthritis, his mother has Marfan syndrome, and a grandmother has had rheumatic fever.
On physical examination, the boy appears uncomfortable. His temperature is 38.9°C (102.0°F) orally, pulse is 90 beats/min, respirations are 20 breaths/min, and blood pressure is 115/58 mm Hg. Remarkable findings include mild pain on full abduction of his right shoulder; a slightly swollen but nontender left ankle; and a markedly swollen right knee that has limited flexion, is exquisitely tender, and has an area of salmon-colored macular erythema over the patella that fades within the hour.
Laboratory results include white blood cell count, 10.5
109/L (10,500/cu mm), with 8% band forms, 74% segmented
neutrophils, 9% lymphocytes, and 9% monocytes; hemoglobin, 144
g/L (14.4 g/dL); platelet count,
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