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(Pediatrics in Review. 2006;27:36-37.)
© 2006 American Academy of Pediatrics

In Brief

Infant Botulism

The first 20% of the full text of this article appears below.

Infant Botulism. Cox N, Hinkle R. Am Fam Physician. 2002;65:1388–1390

Infant Botulism. Long SS.Pediatr Infect Dis J. 2001;20:707–709

Infant Botulism—New York City 2001–2002. Morbidity and Mortality Weekly Report—CDC. JAMA. 2003;289:834–836

Risk of Infant Botulism from Corn Syrup. Olsen SJ, Swerdlow DL. Pediatr Infect Dis J. 2000;19:584

Botulism is a potentially lethal neuroparalytic disorder caused by the toxins produced by Clostridium botulinum. In the United States, most cases of botulism occur in infants, with an incidence of approximately two cases per 100,000 live births. Although infant botulism is rare, timely diagnosis is essential because 50% to 70% of affected infants may require mechanical ventilation.

C botulinum is an ubiquitous gram-positive, anaerobic, spore-forming organism found in soil, marine animals, and bird intestines. Humans can acquire botulism when a wound is infected by the spores or contaminated foods are ingested. Although . . . [Full Text of this Article]

Wanessa Risko, MD, DSc
Boston Children’s Hospital
Harvard Medical School
Boston, Mass