Pediatrics in Review
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(Pediatrics in Review. 2006;27:113-114.)
© 2006 American Academy of Pediatrics


In Brief

Secondary Amenorrhea

The first 20% of the full text of this article appears below.

Menstrual Cycle Abnormalities: Diagnosis and Management. Iglesias E, Coupey S. Adolescent Medicine: State of the Art Reviews. 1999;10 :255 –273

Medical Concerns of the Female Athlete. Pediatrics. 2000;106 :610 –613[Abstract/Free Full Text]

Eating Disorders in Adolescents and Young Adults. Kreipe R, Mou SM. Obstet Gynecol Clin North Am. 2000;27 :101 –124[Medline]

The Female Athlete Triad: Disordered Eating, Amenorrhea, Osteoporosis. Yeager KK, Agostini R, Nattiv A, Drinkwater B. Med Sci Sports Exerc. 1993;25 :775 –777[CrossRef][Medline]

Secondary amenorrhea, the cessation of previously normal menstruation, should be considered in any female who has a gynecologic age of at least 24 months and has not menstruated for three or more consecutive cycles. The gynecologic age, the time in months since menarche, is the best indicator that a normal ovulatory pattern should have been established; regular monthly cycles are not reliably present until 2 years after menarche. The underlying causes of secondary amenorrhea can be understood from a review of the normal menstrual cycle.

The menstrual cycle is regulated by interplay . . . [Full Text of this Article]


Diane Bloomfield, MD
Children’s Hospital at Montefiore Bronx, NY






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