Pediatrics in Review
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(Pediatrics in Review. 2006;27:118-119.)
© 2006 American Academy of Pediatrics

In Brief

Egg-based Vaccines

The first 20% of the full text of this article appears below.

Safe Administration of the Measles Vaccine to Children Allergic to Eggs. James JM, Burks AW, Roberson PK, Sampson HA. N Engl J Med. 1995;332 :1262 –1266[Abstract/Free Full Text]

Safe Administration of Influenza Vaccine to Patients With Egg Allergy. James JM, Zeiger RS, Lester MR, et al. J Pediatr. 1998;133 :6240 –6248

Immunization of Egg-allergic Individuals With Egg- or Chicken-derived Vaccines. Kelso JM, Yuniginger JW. Immunol Allergy Clin North Am. 2003;23 :635 –648[CrossRef][Medline]

Prevalence of Anti-gelatin IgE Antibodies in People With Anaphylaxis After Measles-Mumps-Rubella Vaccine in the United States. Pool V, Braun MM, Kelso JM, et al. Pediatrics. 2002;110 :e71

Egg-containing vaccines present potential risks to children who have an egg allergy. Such vaccines include influenza, measles-mumps-rubella (MMR), rabies, and yellow fever vaccines. Influenza and MMR frequently create concerns due to their recommended administration to all children younger than age 2 years, a period of life when egg allergy is most common. It is important when considering the risk for anaphylaxis to understand both the production methods for these . . . [Full Text of this Article]


Joanne E. Cox, MD
 Boston Children’s Hospital Boston, Mass

Tina L. Cheng, MD, MPH, Associate Editor




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