Pediatrics in Review
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(Pediatrics in Review. 2006;27:155-157.)
© 2006 American Academy of Pediatrics

In Brief

Hyperthyroidism

The first 300 words of the full text of this article appear below.

Thyroid Disorders in Childhood and Adolescence. Fisher DA. In: Sperling MA, ed. Pediatric Endocrinology. 2nd ed. Philadelphia, Pa: WB Saunders; 2002:187 –209

Adolescent Thyroid Disorders. Hanna CE, LaFranchi SH. Adolesc Med. 2002;13 :13 –35

The Spectrum of Thyroid Diseases in Childhood and Its Evolution During Transition to Adulthood: Natural History, Diagnosis, Differential Diagnosis and Management. Koch CA, Sarlis NJ. J Endocrinol Invest. 2001;24 :659 –675

Thyroid Disorders in Children From Birth to Adolescence. Bettendorf M. Eur J Nucl Med Mol Imaging. 2002;29(suppl 2) :S439 -S446

Clinical Review 99: The Management of Graves’ Disease in Children, With Special Emphasis on Radioiodine Treatment. Rivkees SA, Sklar C, Freemark M. J Clin Endocrinol Metab. 1998;83 :3767 –3776

Influence of Iodine-131 Dose on the Outcome of Hyperthyroidism in Children. Rivkees SA, Cornelius EA. Pediatrics. 2003;111 :745 –749

Time Course to Hypothyroidism After Fixed-dose Radioablation Therapy of Graves’ Disease in Children. Nebesio TD, Siddiqui AR, Pescovitz OH, Eugster EA. J Pediatr. 2002;141 :99 –103

Pediatric Graves’ Disease: Outcome and Treatment. Gruneiro-Papendieck L, Chiesa A, Finkielstain G, Heinrich JJ. J Pediatr Endocrinol Metab. 2003;16 :1249 –1255

Graves Disease in Childhood: A Review of the Options for Diagnosis and Treatment. Dotsch J, Rascher W, Dorr HG. Paediatr Drugs. 2003;5 :95 –102

Hyperthyroidism results from overactivity of the thyroid gland. The clinical manifestation of excessive thyroid hormone is thyrotoxicosis, which in more than 95% of childhood and adolescent cases is the consequence of diffuse thyroid hyperplasia (Graves disease). Other causes of thyrotoxicosis include the early phase of autoimmune hypothyroidism (Hashimoto thyroiditis) before thyroid function is diminished; a hyperfunctioning thyroid nodule; pituitary resistance to thyroxine (T4), which results in excessive secretion of thyroid . . . [Full Text of this Article]


Faye Kokotos, MD
 Children’s Hospital at Montefiore Bronx, NY

Henry M. Adam, MD, Editor, In Brief




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