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(Pediatrics in Review. 2006;27:231-237.)
© 2006 American Academy of Pediatrics

Index of Suspicion

The first 300 words of the full text of this article appear below.

Frequently Used Abbreviations

ALT
alanine aminotransferase

AST
aspartate aminotransferase

BUN
blood urea nitrogen

CBC
complete blood count

CNS
central nervous system

CSF
cerebrospinal fluid

CT
computed tomography

ECG
electrocardiography

ED
emergency department

EEG
electroencephalography

ESR
erythrocyte sedimentation rate

GI
gastrointestinal

GU
genitourinary

Hct
hematocrit

Hgb
hemoglobin

MRI
magnetic resonance imaging

WBC
white blood cell


    Case 1 Presentation
 
A 6-year-old boy complains of leg pain during times of inactivity. The pain is diffuse, affects both legs simultaneously, and feels like "pins and needles." The episodes occur intermittently throughout the day and are more intense at night, preventing sleep. In the last week, the discomfort has occurred during sleep, waking him. Massage and movement usually bring relief, with occasional need for acetaminophen.

The episodes began 1 year ago, happened one to two times per month, and now occur several times per week and are more intense. He is noted to be "squirming" while sitting still. His past medical history is free of significant illness, including trauma or sleep disturbances. He is an excellent student. Two aunts suffer from chronic leg pain and associated sleep disturbance.

Physical findings are normal. His legs show no muscle abnormalities, redness, swelling, masses, or pain on palpation. Radiographs of the legs are normal. He has a normal WBC count but has anemia (Hgb 10.4 g/dL [104 g/L]) and iron deficiency (serum ferritin, 40 mcg/L). Red blood cell indices reveal a mean corpuscular volume of 76 fL and mean corpuscular Hgb of 26.4 pg. Antinuclear antibody is negative, and erythrocyte sedimentation rate is 1 mm/h.


    Case 2 Presentation
 
A 2-year-old girl is brought to the ED for sudden loss of consciousness. She has had fever for 2 days, with sore throat, nasal discharge, cough, and decreased activity. She had a patent ductus arteriosus closed 1 month ago using a catheter closure device, after which . . . [Full Text of this Article]


Kevin Turner, MS, III
Michael Ozaki, MD
Don Hayes, Jr, MD
University of California Irvine School of Medicine, Irvine, Calif.
Huntington Beach, Calif.
University of Wisconsin Hospital and Clinics, Madison, Wisc


Ashraf Harahsheh, MD
Kathleen Moltz, MD
Kavitha Chintala, MD
Stephen Knazik, DO, MBA
Deepak Kamat, MD, PhD
Children’s Hospital of Michigan, Detroit, Mich

Diana Dunnigan, MD
Phoenix Indian Medical Center, Phoenix, Ariz

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Copyright © 2006 by the American Academy of Pediatrics.