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(Pediatrics in Review. 2006;27:314-315.)
© 2006 American Academy of Pediatrics

In Brief

Hallucinogens

The first 20% of the full text of this article appears below.

Hallucinogens. Nichols DE. Pharmacol Ther. 2004;101 :131 –181[CrossRef][Medline]

National Institute on Drug Abuse Web Site. Available at http://www.drugabuse.gov

The Psychopharmacology of Hallucinogens. Abraham HD, Aldridge AM, Gogia P. Neuropsychopharmacol. 1996;14 :285 –298[CrossRef][Medline]

Toxic Psychoses as Pharmacological Models of Schizophrenia. Potvin S, Stip E, Roy J. Curr Psychiatr Rev. 2005;1 :23 –32[CrossRef]

The hallucinogens comprise a group of drugs that alters perception, cognition, and mood. Despite their name, hallucinogens only sometimes cause true hallucinations, defined as perceiving experiences that do not occur. These substances exert their mind-altering effects primarily through agonism at serotonin receptors (specifically 5-HT2a) in the central nervous system. There is some controversy over which drugs of abuse fit neatly into the category of hallucinogens. Although phencyclidine (PCP) may cause hallucinations, it is classified as a dissociative drug. Other drugs of abuse such as cocaine, anticholinergics, marijuana, and methylenedioxymethamphetamine (MDMA or "ecstasy") can alter perception or produce hallucinations, but these . . . [Full Text of this Article]


David L. Eldridge, MD
Karin Hillenbrand, MD
 Brody School of Medicine
East Carolina University
Greenville, NC

Janet R. Serwint, MD
 Consulting Editor





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