Pediatrics in Review
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(Pediatrics in Review. 2007;28:e6-e8.)
© 2007 American Academy of Pediatrics

In Brief

Vesicoureteral Reflux

The first 300 words of the full text of this article appear below.

Clinical Significance of Primary Vesicoureteral Reflux and Urinary Antibiotic Prophylaxis After Acute Pyelonephritis: A Multicenter, Randomized, Controlled Study. Garin EH, Olavarria F, Nieto VG, Valenciano B, Campos A, Young L. Pediatrics. 2006;117 :626 –632[Abstract/Free Full Text] Ten-year Results of Randomized Treatment of Children With Severe Vesicoureteral Reflux. Final Report of the International Reflux Study in Children. Jodal U, Smellie JM, Lax H, Hoyer PF. Pediatr Nephrol. 2006;21 :785 –792[CrossRef][Medline] Interventions for Primary Vesicoureteric Reflux. Wheeler DM, Vimalachandra D, Hodson EM, Smith GH, Craig JC. Cochrane Database Syst Rev. 2004;3 :CD001532[Medline] Report on the Management of Primary Vesicoureteral Reflux in Children. Elder JS, Peters CA, Arant BS Jr, et al. Baltimore, Md: American Urological Association, Inc; 1997. Available at: http://www.auanet.org/timssnet/products/guidelines/main_reports/vesi_reflux.pdf Practice Parameter: The Diagnosis, Treatment, and Evaluation of the Initial Urinary Tract Infection in Febrile Infants and Young Children. American Academy of Pediatrics. Committee on Quality Improvement. Subcommittee on Urinary Tract Infection. Pediatrics. 1999;103 :843 –852[Abstract/Free Full Text] Imaging Studies After a First Febrile Urinary Tract Infection in Young Children. Hoberman A, Charron M, Hickey RW, Baskin M, Kearney DH, Wald ER. N Engl J Med. 2003;348 :195 –202[Abstract/Free Full Text]

Vesicoureteral reflux (VUR) is the retrograde flow of urine from the bladder into the ureter and, frequently, the renal collecting system. The presence of VUR is associated with an increased likelihood of pyelonephritis during urinary tract infections (UTIs) that, in turn, may be associated with the development of renal scarring, hypertension, or renal failure.

Primary VUR, which may resolve spontaneously, describes reflux caused by a congenital anatomic deformity of the ureterovesical junction without other urinary tract abnormalities predisposing to VUR. Secondary VUR refers to reflux resulting from increased bladder pressure (eg, posterior urethral valves), abnormal attachment of the . . . [Full Text of this Article]


David G. Bundy, MD, MPH
 Cincinnati Children’s Hospital Medical Center
Cincinnati, Ohio

Janet R. Serwint, MD, Consulting Editor, In Brief




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