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(Pediatrics in Review. 2007;28:164-174.)
© 2007 American Academy of Pediatrics
| The first 300 words of the full text of this article appear below. |
| Objectives |
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| Introduction |
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Gruby, Remak, and Schonlein described the causes of favic tinea in the early 1800s. In the early 1900s, Saboraud classified the dermatophytic fungi. In the 1950s, Kligman further described the natural course and pathogenesis of these infections. In 1958, treatment with oral griseofulvin was introduced, obviating the need to use epilation with radiography or thallium. More recent antifungal medications, the azoles, allylamines, and benzylamines, offer new options of shorter and more convenient dosing regimens.
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Dermatophytes have three genera: Trichophyton, Epidermophyton, and Microsporum. The site of formation of arthroconidia, the spore-forming bodies of the dermatophyte, classifies the species causing tinea capitis. Ectothrix species form conidia around the hair shaft and beneath the cuticle of hair. Endothrix species have arthrospores present within the hair shaft. The favic species have hyphae arranged in parallel within and around the hair shaft. For example, T tonsurans is endothrix, M audouini is ectothrix, and T schoenleinii is favic.
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