Pediatrics in Review
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(Pediatrics in Review. 2007;28:352-354.)
© 2007 American Academy of Pediatrics

In Brief

Measles

The first 300 words of the full text of this article appear below.

Measles. Maldonado Y. In: Long SS, Pickering LK, Prober CG, eds. Principles and Practice of Pediatric Infectious Diseases. 2nd ed. New York, NY: Churchill Livingstone; 2003:1148 –1155 Measles. Katz S. In: Gershon AA, Hotez PJ, Katz SL, eds. Krugman's Infectious Diseases of Children. 11th ed. St. Louis, Mo: Mosby, Inc; 2004:353 –368 Measles. In: Pickering LK, Baker CJ, Long SS, McMillan JA, eds. Red Book: 2006 Report of the Committee on Infectious Diseases. 27th ed. Elk Grove Village, Ill: American Academy of Pediatrics; 2006:441 –452 Measles, Mumps and Rubella –Vaccine Use and Strategies for Elimination of Measles, Rubella and Congenital Rubella Syndrome and Control of Mumps: Recommendations of the Advisory Committee on Immunization Practices. Centers for Disease Control and Prevention. MMWR Morbid Mortal Wkly Rep. 1998;47(No. RR-8) Measles—United States, 2004. Centers for Disease Control and Prevention. MMWR Morbid Mortal Wkly Rep. 2005;54 :1229 –1231[Medline]

Measles is a highly contagious disease characterized by cough, coryza, conjunctivitis, fever, a pathognomonic enanthem (Koplik spots), and a generalized maculopapular rash that starts at the hairline and spreads caudally to the feet. The causative agent is a virus of the genus Morbillivirus, family Paramyxoviridae. An ancient disease, described as long ago as the 7th century AD, measles is endemic worldwide. Even today, although totally preventable by vaccination, hundreds of thousands of deaths from measles occur each year. Prior to the introduction of vaccine in 1963, 3 to 4 million cases occurred annually in the United States, with an average of 450 deaths, most from pneumonia. Epidemic cycles occurred every 2 to 3 years, usually from late winter through early spring. By 15 years of age, 90% of children had contracted the disease. Humans are the only natural host, and the virus is transmitted . . . [Full Text of this Article]


Sara Caldararo, MD
 Albert Einstein College of Medicine
Bronx, NY

Henry M. Adam, MD, Editor, In Brief




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