Pediatrics in Review
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(Pediatrics in Review. 2008;29:410-411. doi:10.1542/10.1542/pir.29-11-410)
© 2008 American Academy of Pediatrics
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In Brief

Listeriosis

The first 20% of the full text of this article appears below.

Ampicillin Use in Infant Fever: A Systematic Review. Brown JC, Burns JL, Cummings P. Arch Pediatr Adolesc Med. 2002;156 :27 –32[Abstract/Free Full Text] An Update on the Medical Management of Listeriosis. Hof H. Expert Opin Pharmacother. 2004;5 :1727 –1735[CrossRef][Medline] Listeriosis. Posfay-Barbe K, Wald E. Pediatr Rev. 2004;25 :151 –159[Free Full Text] Listeriosis: Frequently Asked Questions. Division of Foodborne, Bacterial, and Mycotic Diseases. Available at: http://www.dcd.gov/nczved/dfbmd/disease_listing/listeriosis_gi.html The Epidemiology of Human Listeriosis. Swaminathan B, Gerner-Smidt P. Microbes Infect. 2007;9 :1236 –1243[CrossRef][Medline]

Listeriosis is a rare but potentially serious food-borne infection caused by Listeria monocytogenes, a motile gram-positive bacillus. Listeria can be found throughout the environment in soil, vegetation, water supplies, and animals. The bacterium is particularly suited for food-borne disease because it can survive in acidic and salty conditions. Unlike most pathogens, Listeria can continue to multiply at low temperatures, allowing for growth even in properly refrigerated foods.

After ingestion, the bacillus enters the body through the gastrointestinal tract and disseminates hematogenously. In pregnant women, it can cross the placenta and infect the neonate. Macrophages and other cells endocytose the bacteria, which subsequently multiply and spread directly . . . [Full Text of this Article]


Lara Jacobson, MD
 Baltimore, Md

Janet R. Serwint, MD, Consulting Editor
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Gentamicin and Listeriosis
Leslie L Barton
Pediatrics in Review Online, 7 Jul 2009 [Full text]

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