Pediatrics in Review
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(Pediatrics in Review. 2009;30:187-189. doi:10.1542/10.1542/pir.30-5-187)
© 2009 American Academy of Pediatrics
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In Brief

Joint Problems and Hypermobility

The first 300 words of the full text of this article appear below.

Joint Hypermobility Syndrome in Childhood. A Not So Benign Multisystem Disorder? Adib N, Davies K, Grahame R, et al. Rheumatology. 2005;44 :744 –750[Abstract/Free Full Text]

Ehlers-Danlos Syndromes: Revised Nosology, Villefranche, 1997. Beighton P, De Paepe A, Steinmann B, Tsipouras P, Wenstrup RJ. Ehlers-Danlos National Foundation (USA) and Ehlers-Danlos Support Group. Am J Med Genet. 1998;77 :31 –37[CrossRef][Medline]

Exercise Tolerance in Children and Adolescents with Musculoskeletal Pain in Joint Hypermobility and Joint Hypermobility Syndrome. Engelbert RH, Van Bergen M, Henneken T, et al. Pediatrics. 2006;118 :e690 –e696[Abstract/Free Full Text]

Joint Hypermobility and Fibromyalgia in Schoolchildren. Gedalia A, Press J, Klein M, Buskila D. Ann Rheum Dis. 1993;52 :494 –496[Abstract/Free Full Text]

General Joint Hypermobility and Temporomandibular Joint Derangement in Adolescents. Westling L, Mattiasson A. Ann Rheum Dis. 1992;51 :87 –90[Abstract/Free Full Text]

Musculoskeletal pain is a common complaint in children, and when recurrent, often leads to considerable distress and functional limitation. Inflammatory, infectious, neoplastic, traumatic, and biomechanical diseases make up a vast list of differential diagnoses, but the most common causes of joint pain in children include "growing pains," hypermobility syndromes, patellofemoral syndrome, and pes planus. Typically, these disorders are benign and often self-limiting.

Originally defined by Kirk in 1967, benign joint hypermobility syndrome (BJHS), which also is known as hypermobility syndrome or joint hypermobility syndrome, is recognized as a frequent cause of chronic musculoskeletal pain in children. The syndrome is termed "benign" to distinguish it from inherited connective tissue disorders that may be associated with joint hypermobility. Despite the relatively uncomplicated nature of the disease, identification is essential to avoid unnecessary diagnostic testing, institute appropriate management, and prevent potential future complications.

The prevalence of BJHS ranges from 2% to 30%. The highest frequency is seen in families that have one or more . . . [Full Text of this Article]


Dawn M. Wahezi, MD
Norman Ilowite, MD
 Children's Hospital at Montefiore
Bronx, NY

Henry M. Adam, MD, Editor, In Brief
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