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In Brief

Cleft Palate

The first 300 words of the full text of this article appear below.

Development of the Palate. Moore K, Persaud T. In: The Developing Human. 5th ed. Philadelphia, Pa: WB Saunders Co; 1993

The Oral Cavity: Cleft Lip and Palate. Tinanoff N. In: Behrman R, Kliegman R, Jenson HB, Stanton BF, eds. Nelson Textbook of Pediatrics. 18th ed. Philadelphia, Pa: Saunders Elsevier; 2007:1532

The Multidisciplinary Evaluation and Management of Cleft Lip and Palate. Robin N, Baty H, Franklin J, et al. South Med J. 2006;99 :1111 –1120[Medline]

Craniofacial, Cleft Palate. Witt PF. eMedicine Specialties, Plastic Surgery, Craniofacial. 2006. Available at: http://www.emedicine.com/plastic/TOPIC519.HTM

Cleft Lip/Cleft Palate. Healthinfo. Children's Hospital, St. Louis. 2007. Available at: http://www.stlouischildrens.org/tabid/88/itemid/2526/Cleft-Lip–Cleft-Palate.aspx

Cleft Palate Foundation Website. Available at: http://www.cleftline.org/

Feeding Your Baby With a Cleft Palate Video. Moses M, Alexander ME. New Orleans, La: Cleft & Craniofacial Team of New Orleans. Available at: http://www.neworleanscleftteam.org/videos.html

Cleft palate (CP) is a relatively common birth defect throughout the world. However, it is important to distinguish between cleft palate alone (CPA) and cleft lip with or without cleft palate (CLP), two distinct birth defects that have different causes, incidences, and sex and racial predilections. For example, in the Caucasian population, the incidence of CLP is about 1 in 750 births and that of CPA is about 1 in 2,500. CLP is more common in males; CPA is more common in females. The distribution of CPA varies slightly in different ethnic groups, but is significantly different for CLP, which is most common in Native Americans (1 in 230 to 1,000) and Asians (1 in 400 to 850) and least common in African Americans (1 in 1,300 to 5,000).

The incidence of concurrent genetic disorders is increased for children who have CLP and even higher in those born having CPA. More than 200 genetic syndromes have . . . [Full Text of this Article]

Joy Samanich, MD
Children's Hospital at Montefiore
Bronx, NY

Henry M. Adam, MD, Editor, In Brief

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