HOME HELP CONTACT US SUBSCRIPTIONS CME ARCHIVE SEARCH		QUICK SEARCH:   [advanced] Author: Keyword(s): Year:  Vol:  Page:

Rapid Response to:

Articles: Anne A. Gershon Varicella-Zoster Virus Infections Pediatrics in Review 2008; 29: 5-11 [Full text] [PDF]

Rapid Responses: Submit a response to this article

Rapid Responses published:

Re: Drug clarification

Lawrence F Nazarian   (5 February 2008)

Drug clarification

Jonathen Bartholomew   (5 February 2008)

Re: Drug clarification 5 February 2008
Lawrence F Nazarian, Editor-in-Chief Pediatrics in Review Send letter to journal: Re: Re: Drug clarification sydney_sutherland{at}urmc.rochester.edu Lawrence F Nazarian	In this article, the oral dose of acyclovir for children is given as 20 mg/kg qid. To clarify, the dosage is 20 mg/kg per dose qid. The dosage recommended in the article for adolescents is 4000 mg/day and is based on the treatment for adults who have zoster. The Red Book (AAP, 27th edition, 2006: pg 785) cites a dosage of 800 mg qid (3200 mg/day) for adolescents, and the author recommends using that dosage, although there should be no significant clinical difference between the two regimens. Acyclovir comes in 800 mg tablets. Patients at serious risk for or who have severe or potentially severe infections should be treated with intravenous acyclovir. LFN, Editor, PIR Conflict of Interest: None declared
Drug clarification 5 February 2008
Jonathen Bartholomew, Pediatrician UVRMC Send letter to journal: Re: Drug clarification jbartholomew{at}hotmail.com Jonathen Bartholomew	for the line: The oral dose is 20 mg/kg qid for children Is it divided qid or 20mg/kg/dose qid? Conflict of Interest: None declared