Table 7.

Liquid Jet Injection in the Global Context

Disposable syringe jet injectors (DSJI) may play a critical role in global polio eradication efforts. Inactivated polio virus (IPV) would likely represent a preferred alternative to oral polio virus (OPV) because it is a killed virus and has demonstrated increased immunogenicity in areas where repeated OPV has failed to achieve adequate immunity in the community. Although IPV’s high cost (20 times higher than OPV’s cost) remains a major obstacle, it would be preferred to OPV because it contains killed virus (no risk of vaccine-derived virus transmission) and has demonstrated increased immunogenicity in areas where repeated OPV has failed to achieve adequate immunity in the community. (32)
  • Investigators in Oman have found that using just 20% of the standard IPV by jet injection induced similar levels of seroconversion as intramuscularly administered IPV in 400 infants. (33)

  • Although an earlier study in Cuba reported mild redness and induration in some infants, (34) 93% of parents in the Oman study preferred the DSJI method because of the simple observation that “the baby does not cry.”

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Disposable syringe jet injector use in action (Program for Appropriate Technology in Health, Patrick McKern. All rights reserved.)