Varicella-Zoster Immune Globulin

Michelle Hudspeth

doi:10.1542/pir.26-9-348

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Michelle Hudspeth, MD

Johns Hopkins Hospital
Baltimore, Md

Varicella. American Academy of Pediatrics. In: Pickering LK, ed. Red Book: 2003 Report of the Committee on Infectious Diseases. 26th ed. Elk Grove Village, Ill: American Academy of Pediatrics; 2003:672– 686

Prevention of Varicella. Recommendations of the Advisory Committee on Immunization Practices. Centers for Disease Control and Prevention. Morbid Mortal Wkly Rep MMWR. 1996;45(No. RR-11) :1– 36OpenUrl

Prevention of Varicella. Updated Recommendations of the Advisory Committee on Immunization Practices (ACIP). Centers for Disease Control and Prevention. Morbid Mortal Wkly Rep MMWR Recomm Rep. 1999;48(RR-6) :1– 5OpenUrl

Varicella-zoster virus (VZV) is a highly contagious member of the herpesvirus family. It is spread when the virus comes into contact with conjunctiva or the mucosa of the upper respiratory tract. Routes of person-to-person transmission include direct contact with infected persons and aerosolized droplets from respiratory tract secretions. In addition, maternal varicella infection can lead to in utero infection through transplacental passage of the virus.

The typical incubation period for varicella …