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American Academy of Pediatrics
In Brief

Listeriosis

Lara Jacobson
Pediatrics in Review November 2008, 29 (11) 410-411; DOI: https://doi.org/10.1542/pir.29-11-410
Lara Jacobson
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  1. Lara Jacobson, MD
  1. Baltimore, Md

Ampicillin Use in Infant Fever: A Systematic Review. Brown JC, Burns JL, Cummings P. Arch Pediatr Adolesc Med. 2002;156 :27– 32OpenUrlCrossRefPubMedAn Update on the Medical Management of Listeriosis. Hof H. Expert Opin Pharmacother. 2004;5 :1727– 1735OpenUrlCrossRefPubMedListeriosis. Posfay-Barbe K, Wald E. Pediatr Rev. 2004;25 :151– 159OpenUrlFREE Full TextListeriosis: Frequently Asked Questions. Division of Foodborne, Bacterial, and Mycotic Diseases. Available at: http://www.dcd.gov/nczved/dfbmd/disease_listing/listeriosis_gi.htmlThe Epidemiology of Human Listeriosis. Swaminathan B, Gerner-Smidt P. Microbes Infect. 2007;9 :1236– 1243OpenUrlCrossRefPubMed

Listeriosis is a rare but potentially serious food-borne infection caused by Listeria monocytogenes, a motile gram-positive bacillus. Listeria can be found throughout the environment in soil, vegetation, water supplies, and animals. The bacterium is particularly suited for food-borne disease because it can survive in acidic and salty conditions. Unlike most pathogens, Listeria can continue to multiply at low temperatures, allowing for growth even in properly refrigerated foods.

After ingestion, the bacillus enters the body through the gastrointestinal tract and disseminates hematogenously. In pregnant women, it can cross the placenta and infect the neonate. Macrophages and other cells endocytose the bacteria, which subsequently multiply and spread directly to other macrophages. The …

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Pediatrics in Review: 29 (11)
Pediatrics in Review
Vol. 29, Issue 11
November 2008
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Listeriosis
Lara Jacobson
Pediatrics in Review Nov 2008, 29 (11) 410-411; DOI: 10.1542/pir.29-11-410

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Listeriosis
Lara Jacobson
Pediatrics in Review Nov 2008, 29 (11) 410-411; DOI: 10.1542/pir.29-11-410
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