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- Susan Guralnick, MD
- Stony Brook University Medical Center
Stony Brook, NY
Cholelithiasis is an uncommon occurrence in healthy children, with an incidence ranging from 0.15% to 0.22%. The condition is seen more frequently in children who have certain predisposing conditions. Cholelithiasis can occur at any age, including prenatally, but is most common during puberty. Females are at significantly higher risk, with an overall 4:1 female-to-male predominance that increases to 11 to 22:1 during adolescence.
Gallstones form when bile is supersaturated with cholesterol or bilirubin to the point that the substances no longer are soluble. This effect, along with bile stasis, allows the cholesterol or calcium bilirubinate crystals to remain in the gallbladder (or ductal system for brown stones) long enough to …
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