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- Leonardo R. Brandao, MD, MSc*
- George B. Segel, MD†
- *Assistant Professor of Paediatrics, Division of Haematology/Oncology, University of Toronto, The Hospital for Sick Children, Toronto, Ontario
- †Professor of Medicine, Professor Emeritus of Pediatrics, University of Rochester School of Medicine, Rochester, NY
Author Disclosure
Drs Brandao and Segel have disclosed no financial relationships relevant to this article. This commentary does not contain a discussion of an unapproved/investigative use of a commercial product/device.
Question
A 17-year-old girl meets with you to discuss her use of oral contraceptives (OCPs) that contain estrogen. In the family history focusing on evidence of thrombophilia, you find that the patient’s father died of a pulmonary embolus after disembarking from a transatlantic airplane flight. The patient and her mother want to know if she should use OCPs. The girl is leaving for college, and there is concern for an unwanted pregnancy on the one hand and the risk of thrombosis on the other. How should you advise her?
Answer
In this case, the family history provides a vital piece of information in assessing risk of thrombosis for this patient using OCPs. The current guidelines of the American College of Obstetrics and Gynecology do not …
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