Table 3.

Common Causes of Drug Fever

ClassDrugs
Antimicrobial agentsAcyclovir, carbapenems, cephalosporins, tetracyclines, mebendazole, nitrofurantoin, penicillins, rifampin, sulfonamides, vancomycin
AnticonvulsantsBarbiturates, carbamazepine, phenytoin
AntidepressantsDoxepin, nomifensine
Antineoplastic agents6-mercaptupurine, bleomycin, chlorambucil, cisplatin, cytosine arabinoside, daunorubicin, hydroxyurea, interferon, L-asparaginase, procarbazine, streptozocin, vincristine
Cardiovascular drugsClofibrate, diltiazem, dobutamine, furosemide, heparin, hydralazine, hydrochlorothiazide, methyldopa, oxprenolol, procainamide, quinidine, triamterene
Histamine-2 blockersCimetidine, ranitidine
ImmunosuppressantsAzathioprine, everolimus, mycophenolate mofetil, sirolimus
Nonsteroidal anti-inflammatory drugsIbuprofen, sulindac, phenothiazines, salicylates
OtherAllopurinol, antihistamines, folate, herbal remedies, iodide, metoclopramide, piperazine, propylthiouracil, prostaglandin E2, ritodrine, sulfasalazine, sympathomimetics, theophylline, thyroxine