Table 1.

Frequency of Unintentional/Therapeutic Error Ingestions of Over-the-Counter (OTC) Cough and Cold Medication (CCM) Compared With Other Pharmaceuticals

Unintentional General Ingestions
Age Group2005–20062009–2010Percent Change for OTC CCMsP
OTC CCMsOther PharmaceuticalsOTC CCMsOther Pharmaceuticals
< 2 y15,294295,1559170319,349−40.0< .0001
2–5 y62,934560,87542,503640,966−32.5< .0001
6–12 y310038,873249541,721−19.5< .0001
Total81,328894,90354,1681,002,036−33.4< .0001
Therapeutic Error Ingestions
Age Group2005–20062009–2010Percent Change for OTC CCMsP
OTC CCMsOther PharmaceuticalsOTC CCMsOther Pharmaceuticals
< 2 y12,67247,707311253,051−75.4< .0001
2–5 y21,71549,01811,79357,458−45.7< .0001
6–12 y981548,827895858,087−8.7< .0001
Total44,202145,55223,863168,596−46.0< .0001
  • Statistically significant declines in the unintentional ingestions and therapeutic errors reported to U.S. Poison Control Centers were seen after the U.S. Food and Drug Administration changes in recommendations for use. From Mazer-Amirshahi M, et al. (5) Used with permission from Mosby, Inc.